Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161939 | 0.89 | TSHR (0.39) | TSHRALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL9697877 | 0.88 | TSHR (0.34) | TSHR | |
| SCHEMBL8865298 | 0.81 | EPHX2 (0.43) | TSHRMAPT | |
| SCHEMBL22508819 | 0.80 | EPHX2 (0.46) | TSHRALDH1A1MAPT | |
| SCHEMBL9697580 | 0.78 | CASP1 (0.37) | TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9697817 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL1162314 | 0.75 | TSHR (0.37) | TSHRALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL21674360 | 0.73 | L3MBTL1 (0.38) | TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7399794 | 0.72 | MAPT (0.39) | TSHRALDH1A1MAPTCACNA1BAPBA1 | |
| SCHEMBL9698950 | 0.72 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |