Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 14/20 | 0.52 |
| ▸ | CNR2 | P34972 | 12/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17463438 | 0.93 | LTA4H (0.52) | NR5A1CNR1CNR2LTA4HTP53 | |
| SCHEMBL27574766 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL4417414 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL8889344 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL11802130 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL11806779 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL6816991 | 0.89 | NR5A1 (0.66) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL17204428 | 0.87 | ELANE (0.54) | NR5A1CNR1CNR2LTA4HTP53 | |
| SCHEMBL12550198 | 0.87 | PLA2G2A (0.59) | NR5A1CNR1CNR2PLA2G2ALTA4H | |
| SCHEMBL1070543 | 0.87 | TP53 (0.56) | NR5A1PLA2G2ALTA4HTP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |