Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575589 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL25103790 | 0.93 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL21872432 | 0.93 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL18912152 | 0.93 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL19575423 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL19575583 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL10086228 | 0.89 | KDM1A (0.38) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL24165493 | 0.89 | KDM1A (0.38) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL18379139 | 0.89 | KDM1A (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL13200791 | 0.89 | ALDH1A1 (0.60) | ALDH1A1HSD17B10THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034836-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| US-5109013-A | 2-(2-substituted aminoethyl)-1,4-dialkyl-3,4-dihydro-1H-1,3,5]triazepino[3,2-a]benzimidazol-5(2H)-ones as muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-28 | — | — | US | disclosed |