Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834021 | 0.89 | CHRNA4 (0.39) | CHRNB2CHRNA4CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7792818 | 0.88 | CHRNA4 (0.38) | CHRNB2CHRNA4CHRM2CHRM4CHRM1 | |
| SCHEMBL2420280 | 0.71 | — | — | |
| SCHEMBL9962908 | 0.71 | — | — | |
| SCHEMBL7438188 | 0.71 | — | — | |
| SCHEMBL7318990 | 0.71 | — | — | |
| SCHEMBL7445339 | 0.67 | — | — | |
| SCHEMBL12614597 | 0.67 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM1 | |
| SCHEMBL14111918 | 0.67 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM1 | |
| SCHEMBL12665769 | 0.67 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091397-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0363085-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-04-11 | — | — | EP | disclosed |