Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545846 | 1.00 | PREP (0.61) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL10882017 | 1.00 | PREP (0.61) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL7265704 | 1.00 | PREP (0.61) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL7265619 | 0.96 | PREP (0.57) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL11760193 | 0.96 | PREP (0.57) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL8056455 | 0.96 | PREP (0.57) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL10416187 | 0.93 | PREP (0.65) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL3469545 | 0.93 | PREP (0.65) | PREPCTSLFKBP1AKLK5CMA1 | |
| SCHEMBL8366717 | 0.91 | CMA1 (0.65) | CTSLFKBP1AKLK5CMA1 | |
| SCHEMBL7305436 | 0.91 | CMA1 (0.65) | CTSLFKBP1AKLK5CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004370-A1 | MODIFIED DI- AND TRIPEPTIDYL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-03-19 | — | — | WO | disclosed |