Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736515 | 0.88 | SOAT1 (0.40) | SOAT1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9698693 | 0.86 | SOAT1 (0.49) | SOAT1 | |
| SCHEMBL9699234 | 0.83 | SOAT1 (0.43) | SOAT1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL9738043 | 0.82 | SOAT1 (0.48) | SOAT1ALDH1A1TSHR | |
| SCHEMBL9852391 | 0.82 | SOAT1 (0.42) | SOAT1ALDH1A1HPGDNPSR1 | |
| SCHEMBL9700239 | 0.82 | SOAT1 (0.47) | SOAT1ALDH1A1TSHR | |
| SCHEMBL9700086 | 0.82 | SOAT1 (0.47) | SOAT1ALDH1A1TSHR | |
| SCHEMBL9698751 | 0.81 | SOAT1 (0.50) | SOAT1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9698703 | 0.80 | SOAT1 (0.49) | SOAT1 | |
| SCHEMBL9698127 | 0.79 | SOAT1 (0.64) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |