SCHEMBL9698693

SCHEMBL9698693

CC1(COCCOCc2ccccc2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)n2Cc2ccccc2)OC1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 13/20 0.49
CFTR P13569 1/20 0.33
NR4A2 P43354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852391 0.87 SOAT1 (0.42) SOAT1CFTR
SCHEMBL9700086 0.86 SOAT1 (0.47) SOAT1
SCHEMBL9700239 0.86 SOAT1 (0.47) SOAT1
SCHEMBL9699277 0.86 SOAT1 (0.48) SOAT1
SCHEMBL9698703 0.85 SOAT1 (0.49) SOAT1
SCHEMBL9738043 0.83 SOAT1 (0.48) SOAT1
SCHEMBL9699234 0.83 SOAT1 (0.43) SOAT1
SCHEMBL9700192 0.83 SOAT1 (0.43) SOAT1CFTR
SCHEMBL9700121 0.83 SOAT1 (0.43) SOAT1CFTR
SCHEMBL9700095 0.83 SOAT1 (0.43) SOAT1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017470-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-10-15 WO disclosed
EP-0506437-A1 Imidazoles RHONE POULENC RORER LIMITED (GB) 1992-09-30 EP disclosed