Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 12/20 | 0.48 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698799 | 0.87 | SOAT1 (0.61) | SOAT1ACAT1 | |
| SCHEMBL9697893 | 0.87 | SOAT1 (0.49) | SOAT1ACAT1KCNH2 | |
| SCHEMBL9697934 | 0.87 | SOAT1 (0.64) | SOAT1ACAT1 | |
| SCHEMBL9697918 | 0.87 | SOAT1 (0.64) | SOAT1ACAT1 | |
| SCHEMBL9697928 | 0.86 | SOAT1 (0.65) | SOAT1ACAT1 | |
| SCHEMBL9700155 | 0.86 | SOAT1 (0.65) | SOAT1ACAT1 | |
| SCHEMBL9698693 | 0.83 | SOAT1 (0.49) | SOAT1 | |
| SCHEMBL9699277 | 0.82 | SOAT1 (0.48) | SOAT1ALDH1A1TSHR | |
| SCHEMBL9698951 | 0.81 | SOAT1 (0.53) | SOAT1ACAT1KCNH2ALDH1A1LMNA | |
| SCHEMBL9698895 | 0.81 | SOAT1 (0.53) | SOAT1ACAT1KCNH2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |