Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737457 | 0.88 | SOAT1 (0.48) | CFTRSOAT1ALDH1A1LMNARECQL | |
| SCHEMBL9697997 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9700146 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9700121 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9700192 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9697807 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9700095 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9698755 | 0.83 | SOAT1 (0.43) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9737635 | 0.83 | SOAT1 (0.38) | CFTRSOAT1ALDH1A1PDE6DALDH2 | |
| SCHEMBL9737622 | 0.83 | SOAT1 (0.37) | CFTRSOAT1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |