Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697794 | 0.92 | CASP1 (0.36) | CASP1ERN1ALDH1A1 | |
| SCHEMBL9697580 | 0.88 | CASP1 (0.37) | CASP1MEN1KMT2AERN1MAPT | |
| SCHEMBL9697565 | 0.87 | CASP1 (0.32) | CASP1MEN1KMT2AERN1ALDH1A1 | |
| SCHEMBL9698944 | 0.80 | TSHR (0.32) | CASP1MEN1KMT2AERN1ALDH1A1 | |
| SCHEMBL9697624 | 0.79 | ACHE (0.35) | ERN1ALDH1A1 | |
| SCHEMBL13055388 | 0.75 | MAPT (0.42) | CASP1MEN1KMT2AERN1MAPT | |
| SCHEMBL14073941 | 0.74 | TDP1 (0.42) | MEN1KMT2AMAPT | |
| SCHEMBL9697777 | 0.74 | — | — | |
| SCHEMBL10722194 | 0.74 | CASP1 (0.40) | CASP1MEN1KMT2AERN1MAPT | |
| SCHEMBL31688567 | 0.74 | KMT2A (0.57) | CASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |