⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854293 | 0.71 | — | — | |
| SCHEMBL9298481 | 0.69 | — | — | |
| SCHEMBL6692913 | 0.69 | — | — | |
| SCHEMBL15932255 | 0.65 | — | — | |
| SCHEMBL2407921 | 0.62 | — | — | |
| SCHEMBL9723942 | 0.60 | — | — | |
| SCHEMBL3391323 | 0.60 | HTR1A (0.56) | — | |
| SCHEMBL15853398 | 0.60 | ALDH1A1 (0.40) | — | |
| SCHEMBL1034321 | 0.60 | — | — | |
| SCHEMBL12139950 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135532-A1 | COMPOUNDS FOR THE PREVENTION AND/ OR TREATMENT OF SENESCENT CELL-RELATED PATHOLOGIES AND DISEASES | ISTITUTI CLINICI SCIENTIFICI MAUGERI SPA SB (IT) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023135532-A1 | COMPOUNDS FOR THE PREVENTION AND/ OR TREATMENT OF SENESCENT CELL-RELATED PATHOLOGIES AND DISEASES | ISTITUTI CLINICI SCIENTIFICI MAUGERI SPA SB (IT) | 2023-07-20 | — | — | WO | disclosed |
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |
| US-4820847-A | Process for the preparation of 4-substituted 1-aryl-5-amino-pyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |
| EP-0260521-A1 | Process for the preparation of 4-substituted-1-aryl-5-amino-pyrazoles | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |