SCHEMBL9699505

SCHEMBL9699505

O=[C]CC([C]=O)N1C(=O)C=CC1=O

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.30
GMNN O75496 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
THPO P40225 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15320203 0.72 MGLL (0.40) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL8663722 0.71 CPB2 (0.30)
SCHEMBL21543843 0.68 MGLL (0.34) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL16568461 0.65 MGLL (0.38) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL3683381 0.65 GSK3A (0.32) MGLL
SCHEMBL708908 0.63 MGLL (0.38) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL28568487 0.63 MGLL (0.38) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL11457779 0.61 MGLL (0.42) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL9972351 0.61 MGLL (0.42) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL28949204 0.61 MGLL (0.35) MGLLGMNNALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992005200-A1 XENOBIOTIC-ANTIBODY CONJUGATES CHEMEX PHARMACEUTICALS, INC. (US) 1992-04-02 WO disclosed