Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116638 | 0.91 | LTB4R (0.65) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9699613 | 0.88 | LTB4R (0.59) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL9701722 | 0.87 | LTB4R (0.58) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9119933 | 0.82 | LTB4R (0.61) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9120857 | 0.81 | LTB4R (0.61) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9118843 | 0.81 | LTB4R (0.61) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9120027 | 0.81 | LTB4R (0.60) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL9702002 | 0.80 | LTB4R (0.61) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8994983 | 0.80 | LTB4R (0.59) | LTB4RLTB4R2LMNAKDM4EPOLB | |
| SCHEMBL7711975 | 0.78 | LTB4R (0.72) | LTB4RLTB4R2LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |