Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748091 | 0.90 | LTB4R (0.74) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8747939 | 0.90 | LTB4R (0.74) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8748088 | 0.89 | LTB4R (0.72) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL9699613 | 0.83 | LTB4R (0.59) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| Hydrochloric Acid SCHEMBL9701722 | 0.82 | LTB4R (0.58) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8994937 | 0.82 | PLA2G4B (0.64) | LTB4RMAPTALDH1A1PLA2G4BPPARD | |
| SCHEMBL8747942 | 0.81 | LTB4R (0.53) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL9699596 | 0.80 | LTB4R (0.54) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8994850 | 0.80 | PLA2G4B (0.53) | LTB4RLTB4R2MAPTALDH1A1PLA2G4B | |
| SCHEMBL8995020 | 0.80 | PLA2G4B (0.53) | LTB4RMAPTALDH1A1PLA2G4BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |