Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892928 | 0.87 | TACR1 (0.57) | TACR1TACR3 | |
| SCHEMBL9700982 | 0.84 | CCKBR (0.56) | — | |
| SCHEMBL8893578 | 0.76 | TACR1 (0.51) | TACR1TACR3 | |
| SCHEMBL8894105 | 0.76 | TACR1 (0.51) | TACR1TACR3 | |
| SCHEMBL8894222 | 0.75 | TACR1 (0.48) | TACR1TACR3 | |
| SCHEMBL7665676 | 0.74 | TACR3 (0.43) | TACR1TACR3 | |
| SCHEMBL7672110 | 0.74 | TACR1 (0.54) | TACR1TACR3 | |
| SCHEMBL8894671 | 0.74 | NMBR (0.71) | TACR1TACR3 | |
| SCHEMBL8894285 | 0.74 | NMBR (0.71) | TACR1TACR3 | |
| SCHEMBL8892775 | 0.74 | NMBR (0.71) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |