Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670805 | 0.88 | TACR1 (0.44) | TACR3TACR1NPY5RMMP9 | |
| SCHEMBL7670973 | 0.88 | NPY5R (0.46) | TACR3NPY5R | |
| SCHEMBL9539148 | 0.80 | BLM (0.37) | RIPK1NPY5ROPRM1OPRD1OPRK1 | |
| SCHEMBL8892928 | 0.77 | TACR1 (0.57) | TACR3TACR1 | |
| SCHEMBL9699612 | 0.77 | TACR3 (0.38) | TACR3TACR1 | |
| SCHEMBL9699646 | 0.74 | TACR1 (0.43) | TACR3TACR1 | |
| SCHEMBL9539141 | 0.74 | ITGB3 (0.46) | TACR3TACR1NPY5RLMNA | |
| SCHEMBL9539374 | 0.72 | TACR3 (0.45) | TACR3TACR1NPY5R | |
| SCHEMBL4328760 | 0.72 | BLM (0.57) | OPRM1OPRD1OPRK1BLMLMNA | |
| SCHEMBL31037745 | 0.72 | LMNA (0.47) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | claimed |
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| US-5217957-A | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-06-08 | — | — | US | disclosed |