SCHEMBL9699648

SCHEMBL9699648

CC(Cc1ccc(OCc2ccccc2)cc1)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
CCKBR P32239 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699647 1.00 ITGB3 (0.52) ITGB3ITGA2BCCKBR
SCHEMBL9699654 0.82 ITGB3 (0.52) ITGB3ITGA2B
SCHEMBL9699652 0.82 ITGB3 (0.52) ITGB3ITGA2B
SCHEMBL3350999 0.80 ITGB3 (0.55) ITGB3ITGA2B
SCHEMBL9400094 0.79 CCKBR (0.47) CCKBR
SCHEMBL9699695 0.78 CCKBR (0.55) CCKBR
SCHEMBL9699698 0.78 CCKBR (0.55) CCKBR
SCHEMBL9399428 0.78 CCKBR (0.49) CCKBR
SCHEMBL9700726 0.77 CCKBR (0.46) CCKBR
SCHEMBL9400027 0.75 CCKBR (0.48) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992004025-A1 AMINO ACID ANALOGS AS CCK ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1992-03-19 WO disclosed