Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700754 | 0.84 | PDE3B (0.64) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL9700879 | 0.78 | PSEN1 (0.46) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL9699776 | 0.77 | PDE3B (0.38) | PDE3BPDE3ACRBNTBXAS1CYP11B1 | |
| SCHEMBL9740131 | 0.76 | PDE3B (0.57) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL10463333 | 0.73 | PDE3B (1.00) | PDE3BPDE3ACRBNTBXAS1CYP11B1 | |
| SCHEMBL9088237 | 0.72 | PDE3B (0.66) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL9700740 | 0.71 | PDE3B (0.64) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL27928423 | 0.68 | PDE3B (0.54) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL11709193 | 0.67 | AHR (0.47) | PGRMAPT | |
| SCHEMBL28274911 | 0.67 | PDE3B (0.60) | PDE3BPDE3ACRBNTBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | claimed |
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |