Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.64 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699723 | 0.84 | PDE3B (0.57) | PDE3BPDE3ACRBNTBXAS1TNIK | |
| SCHEMBL10463333 | 0.78 | PDE3B (1.00) | PDE3BPDE3ACRBNTBXAS1TNIK | |
| SCHEMBL9700832 | 0.78 | PSEN1 (0.46) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL9700837 | 0.77 | PDE3B (0.43) | PDE3BPDE3ACRBNTBXAS1CYP11B1 | |
| Hydrochloric Acid SCHEMBL9701788 | 0.77 | PSEN1 (0.45) | PDE3BPDE3ACRBNTBXAS1CYP19A1 | |
| SCHEMBL9700740 | 0.76 | PDE3B (0.64) | PDE3BPDE3ACRBNTBXAS1TNIK | |
| SCHEMBL9088237 | 0.72 | PDE3B (0.66) | PDE3BPDE3ACRBNTBXAS1CYP11B1 | |
| SCHEMBL9740131 | 0.71 | PDE3B (0.57) | PDE3BPDE3ACRBNTBXAS1TNIK | |
| SCHEMBL20777317 | 0.70 | CRBN (1.00) | PDE3BPDE3ACRBNTBXAS1TNIK | |
| SCHEMBL30800784 | 0.70 | CRBN (1.00) | PDE3BPDE3ACRBNTBXAS1TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | claimed |
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |