SCHEMBL9699986

SCHEMBL9699986

O=C(OC(=O)c1c(I)cc(I)c(I)c1I)c1c(I)cc(I)c(I)c1I

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.38
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699996 0.86 LMNA (0.42) TPMTTSHRMAPK1
SCHEMBL31409214 0.81 TPMT (0.52) TPMTTSHRMAPK1
SCHEMBL4277000 0.81 TPMT (0.52) TPMTTSHRMAPK1
SCHEMBL31232360 0.74 TPMT (0.39) TPMTTSHRMAPK1
SCHEMBL25779937 0.74 TPMT (0.39) TPMTTSHRMAPK1
SCHEMBL26028562 0.73 NR1H2 (0.38) TSHR
SCHEMBL8752081 0.73 ESR1 (0.58) TSHRMAPK1
SCHEMBL9717764 0.71 LMNA (0.38) TSHR
SCHEMBL377395 0.70 MAPK1 (0.53) TPMTTSHRMAPK1
Hydrochloric Acid SCHEMBL11407766 0.69 MAPK1 (0.52) TPMTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed