Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717761 | 0.85 | LMNA (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9387753 | 0.82 | CFTR (0.41) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| Butanedione SCHEMBL27926797 | 0.74 | LMNA (0.44) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6012587 | 0.74 | LMNA (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL29394151 | 0.74 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL124763 | 0.74 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717766 | 0.73 | LMNA (0.39) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL11821639 | 0.73 | SERPINE1 (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL10826112 | 0.72 | LMNA (0.39) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL22991595 | 0.72 | LMNA (0.36) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | disclosed |