Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560102 | 0.88 | MCL1 (0.53) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL8959175 | 0.85 | CA2 (0.63) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL8959195 | 0.83 | CA2 (0.61) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL8959243 | 0.82 | CA2 (0.59) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL23748642 | 0.82 | CA1 (0.44) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL31010734 | 0.81 | CA1 (0.42) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL11586010 | 0.80 | CA2 (0.57) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL10990333 | 0.79 | CA2 (0.55) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL4484847 | 0.78 | CA2 (0.46) | CA2CA1ALDH1A1MAPTKMT2A | |
| SCHEMBL4402699 | 0.77 | GPR55 (0.55) | CA2CA1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505923-A1 | Phenol ethers, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1992-09-30 | — | — | EP | disclosed |