SCHEMBL9700175

SCHEMBL9700175

CC(C)(C)NS(=O)(=O)c1ccccc1CCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.44
CA12 O43570 1/20 0.40
ALOX5AP P20292 5/20 0.40
FEN1 P39748 5/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 1/20 0.40
PARG Q86W56 1/20 0.40
USP30 Q70CQ3 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.37
MMP3 P08254 1/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19538861 0.83 NSD2 (0.44) NSD2CA12ALOX5APFEN1MAPT
SCHEMBL10688785 0.83 NSD2 (0.44) NSD2CA12ALOX5APFEN1MAPT
SCHEMBL10691035 0.83 NSD2 (0.44) NSD2CA12ALOX5APFEN1MAPT
SCHEMBL2550857 0.83 CYP1A2 (0.45) CA12ALOX5APFEN1LMNAMMP3
SCHEMBL6612130 0.82 NSD2 (0.43) NSD2CA12ALOX5APFEN1MAPT
SCHEMBL3063791 0.81 NSD2 (0.42) NSD2CA12ALOX5APFEN1MAPT
SCHEMBL10692928 0.81 NSD2 (0.42) NSD2ALOX5APFEN1MAPTSMN1; SMN2
SCHEMBL10726774 0.81 NSD2 (0.42) NSD2ALOX5APFEN1MAPTSMN1; SMN2
SCHEMBL28667640 0.80 LMNA (0.42) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL28689042 0.80 ALDH1A1 (0.41) NSD2MAPTSMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992004454-A1 COMPOUNDS AND CONSTRUCTS FOR PRODUCING MALE STERILE PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-19 WO disclosed
US-4770690-A Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
EP-0106512-B1 HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-18 EP disclosed
US-4699650-A Herbicidal ortho-alkyl-and ortho-alkenyl substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-13 US disclosed
US-4678502-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-07 US disclosed
US-4662933-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-05 US disclosed
EP-0106512-A2 Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-25 EP disclosed