Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 5/20 | 0.68 |
| ▸ | HTR2A | P28223 | 5/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | HTR1D | P28221 | 2/20 | 0.68 |
| ▸ | HTR1B | P28222 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329223 | 0.86 | SLC6A4 (0.69) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL9329211 | 0.86 | CYP2D6 (0.81) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL9329737 | 0.86 | HTR2A (0.81) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL8555709 | 0.86 | SLC6A4 (0.69) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL18929855 | 0.85 | SLC6A4 (0.72) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL5362738 | 0.84 | CYP2D6 (0.79) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL5368511 | 0.84 | CYP2D6 (0.79) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL5363947 | 0.84 | CYP2D6 (0.79) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL7819940 | 0.84 | HTR1A (0.79) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL5360884 | 0.84 | CYP2D6 (0.79) | SLC6A4HTR1AHTR2ACYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106850-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-21 | — | — | US | disclosed |