Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3513090 | 0.85 | HTR6 (0.66) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL13331973 | 0.80 | HTR6 (0.56) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL1748266 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL1748023 | 0.80 | HTR6 (0.50) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL5021178 | 0.77 | MAPT (0.51) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL31395716 | 0.77 | HTR6 (0.53) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL31210114 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2AALPGHTR6 | |
| SCHEMBL9683100 | 0.77 | MAPT (0.67) | MAPTMEN1KMT2AALPGALDH1A1 | |
| SCHEMBL9138464 | 0.76 | MAPT (0.73) | MAPTMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL31325569 | 0.76 | MAPT (0.73) | MAPTMEN1KMT2AHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |