Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465858 | 0.85 | MAPT (0.75) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9683242 | 0.85 | MAPT (0.84) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9681781 | 0.83 | MAPT (0.71) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9682067 | 0.80 | MAPT (0.76) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9681394 | 0.80 | MAPT (0.74) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL31210114 | 0.77 | MAPT (0.56) | MAPTL3MBTL1MEN1KMT2AALPG | |
| SCHEMBL9700265 | 0.77 | MAPT (0.56) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9701292 | 0.77 | MAPT (0.74) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9681376 | 0.77 | MAPT (0.46) | MAPTMEN1KMT2AALPGLMNA | |
| SCHEMBL95561 | 0.76 | MAPT (1.00) | MAPTL3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |