⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701271 | 0.83 | PGR (0.32) | — | |
| SCHEMBL7827974 | 0.81 | USP2 (0.31) | — | |
| SCHEMBL27917873 | 0.74 | ACACB (0.31) | — | |
| SCHEMBL26103106 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL9702705 | 0.69 | TP53 (0.30) | — | |
| Hydrochloric Acid SCHEMBL11070506 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL27720005 | 0.68 | — | — | |
| SCHEMBL27702257 | 0.68 | — | — | |
| SCHEMBL1001523 | 0.68 | — | — | |
| SCHEMBL18086541 | 0.67 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |