Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699292 | 0.84 | KDM4E (0.40) | SOAT1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL9698130 | 0.83 | SOAT1 (0.41) | SOAT1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL9700428 | 0.81 | SOAT1 (0.49) | SOAT1 | |
| SCHEMBL9698957 | 0.81 | SOAT1 (0.49) | SOAT1 | |
| SCHEMBL9737635 | 0.80 | SOAT1 (0.38) | SOAT1ALDH1A1KDM4ETSHRCFTR | |
| SCHEMBL9698749 | 0.80 | SOAT1 (0.40) | SOAT1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL9737457 | 0.79 | SOAT1 (0.48) | SOAT1ALDH1A1KDM4ETSHRCFTR | |
| SCHEMBL9697937 | 0.78 | SOAT1 (0.58) | SOAT1 | |
| SCHEMBL9700192 | 0.75 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRPDE6D | |
| SCHEMBL9700095 | 0.75 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ETSHRCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |