Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700545 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL9700517 | 0.83 | KMT2A (0.61) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL10568844 | 0.80 | ADRB2 (0.51) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL9700715 | 0.80 | ADRB2 (0.51) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL9700719 | 0.80 | ADRB2 (0.51) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL9700538 | 0.80 | ADRB2 (0.51) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Dramedilol SCHEMBL2109623 | 0.80 | KMT2A (0.55) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Dramedilol SCHEMBL9699524 | 0.79 | KMT2A (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Dramedilol SCHEMBL9700551 | 0.79 | KMT2A (0.56) | ADRB2ADRB1ADRB3HTR1AADRA2C | |
| Hydrochloric Acid SCHEMBL9700595 | 0.77 | KMT2A (0.54) | ADRB2ADRB1ADRB3HTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082939-A | Pyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1992-01-21 | — | — | US | disclosed |
| US-4873328-A | Process for preparing alkoxyalkylidenehydrazinopyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1989-10-10 | — | — | US | disclosed |