Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562918 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTRAB9ANPC1 | |
| SCHEMBL1319274 | 0.68 | ALDH1A1 (1.00) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL6935947 | 0.67 | GAA (0.56) | ALDH1A1GAAMAPTPOLBPKM | |
| SCHEMBL21839329 | 0.67 | KCNN4 (0.60) | ALDH1A1KCNN4 | |
| SCHEMBL9172014 | 0.66 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTLMNAKCNN4 | |
| SCHEMBL22190875 | 0.64 | MAPT (0.64) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL29581086 | 0.63 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL29712083 | 0.62 | — | — | |
| SCHEMBL926070 | 0.62 | KCNN4 (0.35) | ALDH1A1PKMRAB9AKCNN4 | |
| SCHEMBL16110725 | 0.62 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082939-A | Pyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1992-01-21 | — | — | US | disclosed |
| US-4873328-A | Process for preparing alkoxyalkylidenehydrazinopyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1989-10-10 | — | — | US | disclosed |
| EP-0274409-A2 | Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives | I.S.F. Socièta per Azioni (IT) | 1988-07-13 | — | — | EP | disclosed |
| US-4632982-A | Triphenylmethyl azo and hydrazino substituted pyridazines | I.S.F. S.P.A. (IT) | 1986-12-30 | — | — | US | disclosed |
| US-4575552-A | Process of making ethyl[6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl]hydrazine carboxylate | I.S.F. S.P.A. (IT) | 1986-03-11 | — | — | US | disclosed |
| EP-0124058-A1 | Preparation of a pharmaceutically active pyridazine derivative | I.S.F. Socièta per Azioni (IT) | 1984-11-07 | — | — | EP | disclosed |