Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592495 | 0.91 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9699476 | 0.75 | AGTR1 (0.49) | AGTR1AGTR2ALDH1A1LMNAMAPT | |
| SCHEMBL9529965 | 0.74 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9592385 | 0.73 | AGTR1 (0.76) | AGTR1AGTR2ALDH1A1LMNAMAPT | |
| SCHEMBL9443057 | 0.73 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9592562 | 0.72 | AGTR1 (0.74) | AGTR1AGTR2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL9588802 | 0.72 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9592139 | 0.71 | AGTR1 (0.58) | AGTR1AGTR2ALDH1A1MAPT | |
| SCHEMBL9590611 | 0.71 | AGTR1 (0.76) | AGTR1AGTR2ALDH1A1LMNAMAPT | |
| SCHEMBL9025416 | 0.70 | AGTR1 (0.47) | AGTR1AGTR2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014468-A1 | PSORIASIS TREATMENT | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | disclosed |