Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700745 | 0.79 | CYP1A2 (0.42) | MEN1KMT2ANPC1CYP1A2CYP2C9 | |
| SCHEMBL13925577 | 0.74 | MIF (0.66) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13925571 | 0.74 | MIF (0.66) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7468752 | 0.72 | MIF (0.58) | MIFALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7468742 | 0.72 | MIF (0.58) | MIFALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9163760 | 0.72 | TSHR (0.42) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL13925578 | 0.72 | MIF (0.70) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9701943 | 0.72 | KDM4E (0.38) | KMT2AKDM4E | |
| SCHEMBL8470843 | 0.70 | MIF (0.50) | MIFALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8306398 | 0.70 | MIF (0.50) | MIFALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |