Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400093 | 0.84 | AKR1C3 (0.46) | ALOX5KDM4EL3MBTL1LMNATSHR | |
| SCHEMBL21807392 | 0.79 | FBP1 (0.53) | MEN1KMT2AFFAR4KDM4EL3MBTL1 | |
| SCHEMBL27958054 | 0.79 | MEN1 (0.83) | MEN1KMT2AALOX5KDM4EL3MBTL1 | |
| SCHEMBL28601407 | 0.79 | MEN1 (0.47) | MEN1KMT2AFFAR4ALOX5KDM4E | |
| SCHEMBL1156189 | 0.76 | KMT2A (0.47) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL21875183 | 0.75 | FBP1 (0.49) | MEN1KMT2AFFAR4KDM4EL3MBTL1 | |
| SCHEMBL10125216 | 0.75 | POLB (0.45) | MEN1KMT2AALOX5KDM4EL3MBTL1 | |
| SCHEMBL1156229 | 0.75 | KMT2A (0.62) | MEN1KMT2AFFAR4ALOX5KDM4E | |
| SCHEMBL23219219 | 0.75 | MEN1 (0.58) | MEN1KMT2AALOX5KDM4EL3MBTL1 | |
| SCHEMBL22299930 | 0.75 | KMT2A (0.39) | MEN1KMT2AFFAR4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |