SCHEMBL28601407

SCHEMBL28601407

COC(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c(S(=O)(=O)c2ccc(C)cc2)c1C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALOX5 P09917 5/20 0.43
FFAR4 Q5NUL3 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 2/20 0.39
GLA P06280 1/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 3/20 0.39
TSHR P16473 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGD P15428 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FBP1 P09467 1/20 0.38
UBE2N P61088 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700742 0.79 MEN1 (0.51) MEN1KMT2AALOX5FFAR4CA12
SCHEMBL21807392 0.75 FBP1 (0.53) MEN1KMT2AFFAR4CA12CA1
SCHEMBL27958054 0.74 MEN1 (0.83) MEN1KMT2AALOX5CA2CA9
SCHEMBL10125216 0.71 POLB (0.45) MEN1KMT2AALOX5LMNAKDM4E
SCHEMBL21875183 0.71 FBP1 (0.49) MEN1KMT2AFFAR4CA12CA1
SCHEMBL23219219 0.71 MEN1 (0.58) MEN1KMT2AALOX5PTGS2ALDH1A1
SCHEMBL18584669 0.70 MEN1 (0.54) MEN1KMT2AALOX5FFAR4CA2
SCHEMBL20141417 0.70 MEN1 (0.48) MEN1KMT2AALOX5PTGS2ALDH1A1
SCHEMBL17973534 0.69 CYP2C9 (0.42) MEN1KMT2AALOX5LMNAKDM4E
SCHEMBL16539947 0.69 RAPGEF4 (0.52) MEN1KMT2AALOX5FFAR4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113164571-A Inhibition of ubiquitin-specific peptidase 9X 福马治疗股份有限公司 2021-07-23 CN disclosed