Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | CPA2 | P48052 | 1/20 | 0.33 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700817 | 0.82 | GNPAT (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5053530 | 0.82 | NFKB1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4599093 | 0.82 | NFKB1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4599052 | 0.82 | NFKB1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL10013379 | 0.74 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13394103 | 0.74 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL14577477 | 0.72 | ALDH1A1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3990273 | 0.72 | — | — | |
| SCHEMBL3990272 | 0.72 | — | — | |
| SCHEMBL8509053 | 0.72 | DPP4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005802-A1 | POLYMERIC CARRIERS FOR RELEASE OF COVALENTLY LINKED AGENTS | NEORX CORPORATION (US) | 1992-04-16 | — | — | WO | disclosed |