Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701761 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2PPARDALDH1A1TSHR | |
| SCHEMBL9702696 | 0.94 | LPAR3 (0.47) | LPAR3LPAR2PPARDALDH1A1TSHR | |
| SCHEMBL9701946 | 0.90 | PPARD (0.37) | LPAR3LPAR2PPARDTSHRTDP1 | |
| Water SCHEMBL9701961 | 0.88 | PPARD (0.36) | LPAR3LPAR2PPARDTSHRAOX1 | |
| SCHEMBL2954341 | 0.83 | LPAR3 (0.46) | LPAR3LPAR2PPARDALDH1A1TSHR | |
| SCHEMBL9700821 | 0.79 | PPARD (0.53) | LPAR3LPAR2PPARDALDH1A1TSHR | |
| SCHEMBL9701509 | 0.77 | PPARD (0.47) | LPAR3LPAR2PPARDTSHRTDP1 | |
| SCHEMBL7528050 | 0.77 | LMNA (0.48) | PPARDTSHRLMNA | |
| SCHEMBL2954338 | 0.76 | LPAR3 (0.39) | LPAR3LPAR2PPARDALDH1A1TSHR | |
| SCHEMBL9701504 | 0.76 | PPARD (0.46) | LPAR3LPAR2PPARDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |