Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269550 | 0.80 | POLB (0.55) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL8907781 | 0.80 | MAOB (0.53) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL9272893 | 0.79 | MAOB (0.49) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL9275250 | 0.79 | RXRB (0.53) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL9507898 | 0.77 | PPARG (0.50) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL9699620 | 0.75 | MAOB (0.45) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL8676840 | 0.75 | RXRB (0.71) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL8677714 | 0.74 | PPARG (0.53) | PPARGRXRARXRBRXRGCYP26A1 | |
| SCHEMBL14286080 | 0.73 | CYP26B1 (0.72) | PPARGCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL8674842 | 0.73 | RXRA (0.68) | PPARGRXRARXRBRXRGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006948-A1 | BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-04-30 | — | — | WO | disclosed |