Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510301 | 0.91 | PPARG (0.41) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL8677714 | 0.91 | PPARG (0.53) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL2095481 | 0.84 | RXRA (0.57) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL8676840 | 0.83 | RXRB (0.71) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL14286080 | 0.81 | CYP26B1 (0.72) | PPARGCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL14286212 | 0.79 | CYP26A1 (0.55) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL8674523 | 0.79 | RARA (0.56) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL9275250 | 0.78 | RXRB (0.53) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL9700920 | 0.77 | PPARG (0.46) | PPARGRXRBRXRARXRGCYP26A1 | |
| SCHEMBL9269550 | 0.77 | POLB (0.55) | PPARGRXRBRXRARXRGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555265-A1 | BICYCLO-COMPOUNDS WITH AN ANTI-SEBORRHOEIC ACTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992006946-A1 | BICYCLO-COMPOUNDS WITH AN ANTI-SEBORRHOEIC ACTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-04-30 | — | — | WO | disclosed |