Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592297 | 0.85 | NPC1 (0.54) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1252918 | 0.85 | KMT2A (0.64) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10341802 | 0.83 | NPC1 (0.58) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20511418 | 0.83 | MEN1 (0.62) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9366252 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20495063 | 0.81 | MEN1 (0.59) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL513780 | 0.81 | PTPN1 (0.61) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3957352 | 0.81 | CYP2C19 (0.60) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19246201 | 0.81 | HPGD (0.64) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL514347 | 0.80 | PTPN1 (0.64) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006081-A1 | ANILIDE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |
| US-5045540-A | Amide or urea compounds containing imidazole groups | WARNER-LAMBERT CO. (US) | 1991-09-03 | — | — | US | disclosed |
| US-5041552-A | Treatment of hypertension, heart failure, glaucoma and hyperaldosteronism | WARNER-LAMBERT COMPANY (US) | 1991-08-20 | — | — | US | disclosed |