Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68952 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL29416299 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL2552940 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL30957166 | 0.81 | SIRT3 (0.61) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL1440123 | 0.81 | SIRT3 (0.61) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL5834304 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL14874214 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL3560534 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL2120360 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL5700411 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1GLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |