Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021773 | 0.80 | ALDH1A1 (0.49) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| SCHEMBL9022081 | 0.79 | ALDH1A1 (0.48) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| SCHEMBL9022073 | 0.79 | ALDH1A1 (0.36) | HTTMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL9701679 | 0.74 | MAPT (0.49) | HTTMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL9075439 | 0.70 | ALDH1A1 (0.48) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| Ethametsulfuron Methyl SCHEMBL30116866 | 0.68 | ALDH1A1 (0.59) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| Ethametsulfuron Methyl SCHEMBL55796 | 0.68 | ALDH1A1 (0.59) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| Ethametsulfuron Methyl SCHEMBL29512476 | 0.68 | ALDH1A1 (0.59) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| Ethametsulfuron Methyl SCHEMBL15019468 | 0.67 | MAPT (0.56) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| SCHEMBL8795091 | 0.66 | ALDH1A1 (0.44) | HTTMAPTTP53ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |