SCHEMBL9700985

SCHEMBL9700985

O=C(/C=C\c1ccccn1)c1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.63
TUBB P07437 2/20 0.63
TUBA3C P0DPH7 2/20 0.63
TUBA1B P68363 2/20 0.63
TUBA4A P68366 2/20 0.63
TUBB4B P68371 2/20 0.63
TUBB3 Q13509 2/20 0.63
TUBB2A Q13885 2/20 0.63
TUBB8 Q3ZCM7 2/20 0.63
TUBA3E Q6PEY2 2/20 0.63
TUBA1A Q71U36 2/20 0.63
TUBA1C Q9BQE3 2/20 0.63
TUBB6 Q9BUF5 2/20 0.63
TUBB2B Q9BVA1 2/20 0.63
TUBB1 Q9H4B7 2/20 0.63
TNFRSF1A P19438 1/20 0.57
NFE2L2 Q16236 3/20 0.56
KEAP1 Q14145 2/20 0.56
HSP90AA1 P07900 2/20 0.56
MAPT P10636 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700990 1.00 TUBB4A (0.63) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15882450 0.92 TUBB4A (0.72) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15882451 0.92 TUBB4A (0.72) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Wr-190433 SCHEMBL977482 0.86 TUBB4A (0.66) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Wr-190433 SCHEMBL29870441 0.86 TUBB4A (0.66) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Wr-190433 SCHEMBL6180067 0.86 TUBB4A (0.66) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Wr-190433 SCHEMBL30880222 0.86 TUBB4A (0.66) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11473133 0.85 TUBB4A (0.65) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11473136 0.85 TUBB4A (0.65) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1604279 0.85 TUBB4A (0.65) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992012154-A1 IMIDAZOTRIAZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-23 WO disclosed