SCHEMBL33161

SCHEMBL33161

Nc1ccc(F)c(N)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29487496 1.00
Formic Acid Methyl Ester SCHEMBL15987678 0.81 CASP1 (0.39)
SCHEMBL3789413 0.79 TAAR1 (0.54)
SCHEMBL10926983 0.79 MAPT (0.40)
SCHEMBL29393564 0.79
SCHEMBL9701 0.79
SCHEMBL33738 0.77
SCHEMBL8181149 0.77 TDP1 (0.55)
SCHEMBL112382 0.77
SCHEMBL29415472 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702646-B Fluorenyl-biphenyl type epoxy material with high insulating property and preparation method thereof 合肥工业大学 2024-05-31 CN claimed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-115055066-B Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2023-07-07 CN claimed
CN-112266317-B Process for preparing 1,2, 4-trifluorobenzene 台州臻挚生物科技有限公司 2023-02-10 CN claimed
CN-115055066-A Microporous polymer particle/polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2022-09-16 CN claimed
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
CN-114702646-A Fluorenyl-biphenyl epoxy material with high insulating property and preparation method thereof 合肥工业大学 2022-07-05 CN claimed
CN-113564745-B Polyamide fiber and preparation method thereof 安徽农业大学 2022-06-21 CN claimed
CN-109794166-B Positively charged composite nanofiltration membrane and preparation method thereof 欧美新材料(浙江)有限公司 2021-11-16 CN claimed
CN-109663511-B Composite nanofiltration membrane and preparation method thereof 欧美新材料(浙江)有限公司 2021-11-16 CN claimed
US-9056284-B2 Chlorine resistant amides, polyamides, and membranes made from the same THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2015-06-16 US claimed
US-20140042082-A1 CHLORINE RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR 2014-02-13 US claimed
US-7419656-B2 Mixture containing phenylenediamine compound KAO CORPORATION (JP) 2008-09-02 US claimed
CN-1178898-C Process for preparing N- (3-amino-4-fluorophenyl) sulfonamides, N- (3-amino-4-fluorophenyl) carboxamides and N- (3-amino-4-fluorophenyl) carbamates 2004-12-08 CN claimed
EP-1045829-B1 METHOD FOR PRODUCING N-(3-AMINO-4-FLUOROPHENYL)- SULPHONAMIDES, N-(3-AMINO-4-FLUOROPHENYL) CARBOXYLIC ACID AMIDES AND N-(3-AMINO-4-FLUOROPHENYL) CARBAMATES BAYER CROPSCIENCE AG (DE) 2003-06-04 EP claimed
US-6218565-B1 1-FLUORO-2,4-DIAMINO-BENZENE IS REACTED WITH SULPHONYL CHLORIDES, CARBONYL CHLORIDES OR CHLORORFORMIC ESTERS IN THE PRESENCE OF AN ACID ACCEPTOR AND IN THE PRESENCE OF A DILUENT BAYER AKTIENGESELLSCHAFT (DE) 2001-04-17 US claimed
CN-1285816-A Method for producing N-(3-amino-4-fluorophenyl)-sulphonamides, N-(3-amino-4-fluorophenyl) carboxylic acid amides and N-(3-amino-4-fluorophenyl) carbamates BAYER AG (DE) 2001-02-28 CN claimed
EP-1045829-A1 METHOD FOR PRODUCING N-(3-AMINO-4-FLUOROPHENYL)- SULPHONAMIDES, N-(3-AMINO-4-FLUOROPHENYL) CARBOXYLIC ACID AMIDES AND N-(3-AMINO-4-FLUOROPHENYL) CARBAMATES BAYER AG (DE) 2000-10-25 EP claimed
WO-1999035122-A1 METHOD FOR PRODUCING N-(3-AMINO-4-FLUOROPHENYL)- SULPHONAMIDES, N-(3-AMINO-4-FLUOROPHENYL) CARBOXYLIC ACID AMIDES AND N-(3-AMINO-4-FLUOROPHENYL) CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1999-07-15 WO claimed
US-3965183-A FROM M-NITROACETANILIDE WITH HYDROGEN FLUORIDE OLIN CORPORATION (US) 1976-06-22 US claimed