Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551396 | 0.90 | HTT (0.42) | HTTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7451566 | 0.87 | HTT (0.58) | HTTPOLBKMT2ACA1CA2 | |
| SCHEMBL7450571 | 0.82 | HTT (0.53) | HTTPOLBKMT2AMEN1CA1 | |
| SCHEMBL7448869 | 0.79 | HTT (0.50) | HTTPOLBKMT2ACA1CA2 | |
| SCHEMBL7976000 | 0.79 | HTT (0.50) | HTTKMT2A | |
| SCHEMBL7300749 | 0.78 | TRPA1 (0.41) | ALDH1A1POLBKMT2AMEN1HPGD | |
| SCHEMBL9708802 | 0.78 | TRPA1 (0.41) | ALDH1A1POLBKMT2AMEN1HPGD | |
| SCHEMBL9708851 | 0.78 | TRPA1 (0.41) | ALDH1A1POLBKMT2AMEN1HPGD | |
| SCHEMBL7277789 | 0.78 | TRPA1 (0.41) | ALDH1A1POLBKMT2AMEN1HPGD | |
| SCHEMBL7771507 | 0.78 | BACE1 (0.44) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000948-A1 | INHIBITORS OF RETROVIRAL PROTEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |