Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700688 | 0.87 | BRCA1 (0.44) | PTGDR2MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL9701386 | 0.76 | BRCA1 (0.41) | PTGDR2MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL14470724 | 0.75 | PTGDR2 (0.61) | PTGDR2MEN1CYP3A4MAPTALOX15 | |
| SCHEMBL9701790 | 0.75 | BRCA1 (0.46) | MEN1MAPTKMT2AHSD17B10ALOX5 | |
| SCHEMBL9701766 | 0.75 | KAT2B (0.42) | ICMTALOX5 | |
| SCHEMBL10172212 | 0.71 | PTGDR2 (0.48) | PTGDR2MEN1CYP3A4MAPTALOX15 | |
| SCHEMBL13470741 | 0.69 | PTGDR2 (0.47) | PTGDR2MEN1CYP3A4MAPTALOX15 | |
| SCHEMBL10268362 | 0.69 | CPT1A (0.53) | PTGDR2MEN1CYP3A4MAPTALOX15 | |
| SCHEMBL19340109 | 0.69 | PTGDR2 (0.46) | PTGDR2MEN1CYP3A4MAPTALOX15 | |
| SCHEMBL21027884 | 0.67 | PTGDR2 (0.49) | PTGDR2MEN1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |