Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700688 | 0.87 | BRCA1 (0.44) | BRCA1ALDH1A1SMN1; SMN2KAT2BPOLB | |
| SCHEMBL9701766 | 0.82 | KAT2B (0.42) | BRCA1ALDH1A1SMN1; SMN2KAT2BALOX5 | |
| SCHEMBL9701348 | 0.75 | PTGDR2 (0.54) | MEN1KMT2AHSD17B10ALOX5MAPT | |
| SCHEMBL9701386 | 0.74 | BRCA1 (0.41) | BRCA1ALDH1A1SMN1; SMN2KAT2BPOLB | |
| SCHEMBL9700697 | 0.72 | BRCA1 (0.49) | BRCA1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9701525 | 0.63 | ALDH1A1 (0.44) | BRCA1ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL2395366 | 0.63 | ALOX5 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL5069182 | 0.61 | PLK1 (0.64) | ALDH1A1KAT2BMEN1KMT2AKDM4E | |
| SCHEMBL23956122 | 0.61 | KMT2A (0.55) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL21027633 | 0.61 | KDM4E (0.56) | ALDH1A1POLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |