Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701790 | 0.82 | BRCA1 (0.46) | KAT2BALOX5PLK1ALDH1A1BRCA1 | |
| SCHEMBL9700688 | 0.80 | BRCA1 (0.44) | KAT2BALOX5PLK1ALDH1A1BRCA1 | |
| SCHEMBL9701348 | 0.75 | PTGDR2 (0.54) | ALOX5ICMT | |
| SCHEMBL9703067 | 0.70 | KMT2A (0.48) | ALDH1A1LMNAHTTCNR1CNR2 | |
| SCHEMBL9701386 | 0.67 | BRCA1 (0.41) | KAT2BALOX5PLK1ALDH1A1BRCA1 | |
| SCHEMBL2395366 | 0.65 | ALOX5 (0.53) | ALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL15333488 | 0.65 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTCNR1CNR2 | |
| SCHEMBL8710581 | 0.64 | HTR6 (0.60) | CNR2 | |
| SCHEMBL5069182 | 0.62 | PLK1 (0.64) | KAT2BPLK1ALDH1A1LMNA | |
| SCHEMBL23956122 | 0.62 | KMT2A (0.55) | ALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |