Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309198 | 0.87 | TSHR (0.66) | TSHRHSD17B10CYP3A4LCKFYN | |
| SCHEMBL13579888 | 0.83 | TSHR (0.55) | TSHRHSD17B10CYP3A4LCKFYN | |
| SCHEMBL18309189 | 0.82 | TSHR (0.56) | TSHRHSD17B10CYP3A4LCKFYN | |
| SCHEMBL2833340 | 0.81 | TSHR (0.55) | TSHRHSD17B10CYP3A4TP53KMT2A | |
| SCHEMBL23489015 | 0.80 | KDM4E (0.53) | TSHRHSD17B10LCKFYNTP53 | |
| SCHEMBL18309191 | 0.80 | ALDH1A1 (0.47) | TSHRHSD17B10LCKFYNKDM4E | |
| SCHEMBL70539 | 0.80 | PDE4D (0.47) | TSHRHSD17B10LCKFYNTP53 | |
| SCHEMBL8902058 | 0.80 | HPGD (0.53) | KDM4EALDH1A1HPGDPPARGPPARA | |
| SCHEMBL7797972 | 0.79 | TSHR (0.53) | TSHRHSD17B10CYP3A4LCKFYN | |
| SCHEMBL2828736 | 0.79 | TSHR (0.75) | TSHRHSD17B10CYP3A4LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |