Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606856 | 0.78 | PTPN1 (0.42) | PTPN1APP | |
| SCHEMBL1135286 | 0.78 | PTPN1 (0.39) | PTPN1IDO1 | |
| SCHEMBL2046409 | 0.73 | SMN1; SMN2 (0.44) | PTPN1APP | |
| SCHEMBL6932234 | 0.72 | PTPN1 (0.49) | PTPN1APP | |
| SCHEMBL8787383 | 0.71 | ABCB1 (0.38) | IDO1 | |
| SCHEMBL23884122 | 0.70 | PTPN1 (0.37) | PTPN1APP | |
| SCHEMBL30234366 | 0.70 | PTPN1 (0.37) | PTPN1APP | |
| SCHEMBL24596979 | 0.70 | ALDH1A1 (0.41) | PTPN1APP | |
| SCHEMBL6282108 | 0.67 | PTPN1 (0.37) | PTPN1IDO1 | |
| SCHEMBL18190386 | 0.67 | PTPN1 (0.35) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496548-A1 | Carbacyclin analogs | PURDUE RESEARCH FOUNDATION (US) | 1992-07-29 | — | — | EP | disclosed |