Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374951 | 0.82 | KDM4E (0.68) | FPR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9700696 | 0.79 | KDM4E (0.53) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL3374953 | 0.72 | PDE4B (0.48) | FPR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7411191 | 0.71 | PDE4B (0.63) | FPR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8635605 | 0.71 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL17111303 | 0.70 | HTR2A (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6873365 | 0.70 | ACHE (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4722080 | 0.69 | PDE4D (0.49) | FPR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28324572 | 0.69 | CHRNB4 (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29993440 | 0.69 | CHRNB4 (0.58) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |